Androgen Action 
Diagnosis and Prognosis
Epidemiology, Prevention, and Quality of Life
Clinical Studies Overview
The PCP focuses on understanding the mechanisms responsible for prostate cancer progression, identifying potential targets for more effective therapies, prevention, diagnosis, and prognosis, and developing pre-clinical and clinical trials to evaluate the efficacy of interventions based on such targets. The overall hypothesis linking different PCP research projects is that alterations in different signaling pathways and androgen actions due to genetic, epigenetic and/or environmental factors and their crosstalk play essential roles in prostate cancer development and progression and provide targets for diagnosis, prognosis, and therapy of prostate cancer. The Program has special expertise in prostate cancer biology, androgen action, prevention, urologic surgery, clinical pharmacology, and in developing new drugs and hormone therapies. Program members have been exploring ways to overcome drug resistance to conventional therapies as well as studying the use of novel agents for the treatment of prostate cancer.
