University of Pittsburgh Cancer Institute (UPCI)

Edward Chu, MD (Co-Leader)
Email: chue2@upmc.edu
Research Interests / Keywords:
Cancer pharmacology; cancer drug development; phase I/II clinical trials; drug resistance; regulation of gene expression; translational regulation; Chinese herbal medicine; colorectal cancer; GI cancers

Peter Wipf, PhD (Co-Leader)
Email: pwipf@pitt.edu
Research Interests / Keywords:
Total synthesis of natural products; organometallic and heterocyclic chemistry; combinatorial synthesis

Mounzer Agha, MD
Email: aghame@upmc.edu
Research Interests / Keywords:
Hematopoietic stem cell transplant; hematologic malignancies

Daniel Altschuler, PhD
Email: altschul@pitt.edu
Research Interests / Keywords:
Cancer pharmacology; signal transduction

Carolyn Anderson, PhD
Email: andersoncj@upmc.edu
Research Interests / Keywords:
Designing, synthesizing and evaluating novel molecular imaging agents for cancer and cancer therapy

Leonard Appleman, MD, PhD
Email: applemanlj@upmc.edu
Research Interests / Keywords:
Kidney cancer and other genitourinary malignancies; experimental cancer therapeutics View More

Sanford Asher, PhD
Email: asher@pitt.edu
Research Interests / Keywords:
Amide excited states and protein folding; diamond growth chemistry; materials science and non-linear optics

Nathan Bahary, MD, PhD
Email: baharyn@upmc.edu
Research Interests / Keywords:
Novel treatment strategies for GI cancers; developmental biology using the zebrafish model system; vasculogenesis; hematopoiesis

David Bartlett, MD
Email: bartlettdl@upmc.edu
Research Interests / Keywords:
Viral therapy; GI cancers; surgical oncology View More

Jan-Hendrik Beumer, PharmD, PhD
Email: beumerjh@upmc.edu
Research Interests / Keywords:
Pharmacokinetics and metabolism of anti-cancer drugs; nucleoside analogues and epigenetic drugs

Robert Branch, MD
Email: Branch@dom.pitt.edu
Research Interests / Keywords:
Drug metabolism; pharmacogenetics; pharmacogenomics

Adam Brufsky, MD, PhD
Email: brufskyam@upmc.edu
Research Interests / Keywords:
Breast cancer; clinical trials; molecular biology of breast cancer

Rebecca Crowley, MD, MS
Email: crowleyrs@msx.upmc.edu
Research Interests / Keywords:
Intelligent medical training systems; empirical studies of medical decision making and expertise; image-guided decision support systems; human-computer interaction; multi-institution data and tissue sharing

Dennis Curran, PhD
Email: curran@pitt.edu
Research Interests / Keywords:
Natural products total synthesis; new synthetic methods; stereochemistry

Nancy E. Davidson, MD
Email: davidsonne@upmc.edu
Research Interests / Keywords:
Cancer biology, treatment and policy; breast cancer; novel therapeutics; hormonal regulation of breast cancer growth; estrogen receptor

Billy Day, PhD
Email: bday@pitt.edu
Research Interests / Keywords:
Antitumor, anti-HIV, and organ damage-reversal agent synthesis; radio- and stable isotope-labeled drugs, toxins and metabolites; photoaffinity probes View More

Robert Edwards, MD
Email: rpe1@pitt.edu or edwarp@mail.magee.edu
Research Interests / Keywords:
Ovarian cancer; cervical cancer; intraperitoneal chemotherapy; immunotherapy View More

Julie Eiseman, PhD
Email: eiseman@upmc.edu
Research Interests / Keywords:
Protein kinases and phosphatases; cancer pharmacology

Raymond Felgar, MD, PhD
Email: felgarre@upmc.edu
Research Interests / Keywords:
Classification and pathobiology of hematopoietic and lymphoid malignancies

Paul Floreancig, PhD
Email: florean@pitt.edu
Research Interests / Keywords:
Complex molecule synthesis; organic chemistry

James Gnarra, PhD
Email: gnarraj@pitt.edu
Research Interests / Keywords:
The von Hippel-Lindau (VHL) tumor suppressor; hypoxia-responsive gene products; cell cycle View More

Rakesh Goyal, MD
Email: rakesh.goyal@chp.edu
Research Interests / Keywords:
Genetic variability and outcome of transplant therapy; graft-versus-host disease (GVHD); stem cell transplantation

Susan Greenspan, MD
Email: greenspansl3@upmc.edu
Research Interests / Keywords:
Osteoporosis in elderly men & women; combination therapy for treatment of osteoporosis; osteoporosis in men with prostate cancer View More

Qiuhong He, PhD
Email: heq@upmc.edu
Research Interests / Keywords:
Magnetic resonance imaging (MRI); breast cancer; tumor imaging

Chien Ho, PhD
Email: chienho@andrew.cmu.edu
Research Interests / Keywords:
Cooperative oxygenation of hemoglobin; novel magnetic resonance imaging (MRI) methodologies to monitor immune response in vivo

Matthew Holtzman, MD
Email: holtzmanmp@upmc.edu
Research Interests / Keywords:
Surgical oncology; GI cancers; melanoma; sarcomas; prevention and treatment of recurrent cancers

Yi Huang, PhD
Email: yih26@pitt.edu
Research Interests / Keywords:
Receptor pharmacology; estrogen receptor

Regina Jakacki, MD
Email: Regina.Jakacki@chp.edu
Research Interests / Keywords:
Adolescent and young adult brain tumors; phase I clinical trials; palliative care
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Yu Jiang, PhD
Email: yuj5@pitt.edu
Research Interests / Keywords:
Protein kinases and phosphatases; cancer pharmacology; signal transduction

Daniel Johnson, PhD
Email: johnsond@pitt.edu
Research Interests / Keywords:
Apoptosis; head and neck neoplasms; myeloid and acute leukemia; myeloid differentiation; proteasome inhibitors; autophagy; signal transduction View More

Valerian Kagan, PhD, DSc
Email: kagan@pitt.edu
Research Interests / Keywords:
Free radical biochemistry; phospholipid signaling in cell death pathways; nitric oxide (NO) interactions with cellular components; antioxidant activity of pulmonary epithelial and endothelial proteins

Joseph Kelley, MD
Email: jkelley@mail.magee.edu
Research Interests / Keywords:
Clinical trials for the treatment of gynecologic and breast malignancies

Kazunori Koide, PhD
Email: koide@pitt.edu
Research Interests / Keywords:
Organic synthesis of natural products; new synthetic methods; organic fluorescent sensors

Lakshmanan Krishnamurti, MD
Email: lakshmanan.krishnamurti@chp.edu
Research Interests / Keywords:
Hematopoietic stem cell transplantation; post-transplant lymphoproliferative disorder

Thomas Krivak, MD
Email: tkrivak@mail.magee.edu
Research Interests / Keywords:
Gynecologic oncology

Eric Lagasse, PharmD, PhD
Email: lagasse@pitt.edu
Research Interests / Keywords:
Cancer stem cells; colon cancer; ovarian cancer; head and neck cancer; liver cancer

Sanford Leuba, PhD
Email: leuba@pitt.edu
Research Interests / Keywords:
Regulation of intracellular signaling and gene expression; chromatin; DNA repair; cell cycle control View More

Song Li, MD, PhD
Email: sol4@pitt.edu
Research Interests / Keywords:
Targeted delivery of therapeutics; gene regulation View More

Yang Liu, PhD
Email: LiuY@pitt.edu
Research Interests / Keywords:
Biomedical optical imaging and spectroscopy for early cancer diagnosis, surveillance, and prevention

Jodi Maranchie, MD, FACS
Email: maranchiejk@upmc.edu
Research Interests / Keywords:
Kidney cancer View More

Scott Nelson, PhD
Email: sgnelson@pitt.edu
Research Interests / Keywords:
Asymmetric catalysis; new reaction technology for the rapid and efficient construction of therapeutically relevant compounds

Robert Parker, PhD
Email: rparker@pitt.edu
Research Interests / Keywords:
Cancer tumor growth modeling and optimal therapy; noninvasive measurement of drug pharmacokinetics; empirical model identification and validation; simultaneous process identification and control

Bruce Pitt, PhD
Email: brucep@pitt.edu
Research Interests / Keywords:
Molecular and cellular biology of the lung; gene therapy

Ian Pollack, MD
Email: pollacki@upmc.edu
Research Interests / Keywords:
Pediatric neurosurgery; pediatric neuro-oncology; craniofacial surgery; congenital spinal abnormalities; brain tumor clinical trials
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Douglas Potter, PhD
Email: potter@upci.pitt.edu
Research Interests / Keywords:
Statistical methodology for design and analysis of preclinical studies and early phase clinical trials in cancer; development and use of novel exact and approximate permutation tests; analysis of small datasets
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Edward Prochownik, MD, PhD
Email: procev@chp.edu
Research Interests / Keywords:
Regulation of and by the c-Myc oncoprotein; evaluation of molecular inhibitors of the c-Myc oncoprotein View More

Shannon Puhalla, MD
Email: puhallasl@upmc.edu
Research Interests / Keywords:
Breast oncology; phase I clinical studies; novel therapeutics in breast cancer

Margaret Ragni, MD, MPH
Email: ragni@dom.pitt.edu
Research Interests / Keywords:
Von Willebrand Disease and other bleeding disorders; epidemiology of HIV/HCV infection in hemophilia and liver disease progression; gene therapy

Anastasios Raptis, MD
Email: raptisa@upmc.edu
Research Interests / Keywords:
Hematologic malignancies

Robert Redner, MD
Email: rednerrl@upmc.edu
Research Interests / Keywords:
Acute promyelocytic leukemia; acute myeloid leukemia; myelodysplastic syndromes; malignant and non-malignant hematology View More

A. Kim Ritchey, MD
Email: kim.ritchey@chp.edu
Research Interests / Keywords:
Stress management for families of children with cancer; chronic stress and pro-inflammatory cytokine regulation

Lisa Robinson, MD
Email: robilj@upmc.edu
Research Interests / Keywords:
Molecular hematopathology; cell signaling abnormalities in acute leukemia

Guillermo Romero, PhD
Email: ggr@pitt.edu
Research Interests / Keywords:
Receptor pharmacology; cancer pharmacology; signal transduction

J. Peter Rubin, MD
Email: rubipj@upmc.edu
Research Interests / Keywords:
Stem cell-based therapies; adipose (fat) metabolism View More

John Schmitz, PhD
Email: schmitzjc@upmc.edu
Research Interests / Keywords:
Signal transduction; colorectal cancer; herbal medicine

Robert Schoen, MD, MPH
Email: schoen@dom.pitt.edu
Research Interests / Keywords:
Early detection and prevention of colorectal cancer (CRC); flexible sigmoidoscopy; acceptability and implementation of CRC screening; surveillance colonoscopy; relationship of insulin/insulin-like growth factors to adenomatous polyps and CRC

Peter Shaw, MD
Email: Peter.Shaw@chp.edu
Research Interests / Keywords:
Pediatric oncology; fertility preservation in oncology and bone marrow transplant patients

Ronald Stoller, MD
Email: schore2@upmc.edu
Research Interests / Keywords:
Gastro-malignancies; pancreatic carcinoma; abdominal carcinomatosis; general oncology

Hussein Tawbi, MD
Email: tawbhx@upmc.edu
Research Interests / Keywords:
DNA repair pathways; chemotherapy resistance; clinical trials

Mohamed Virji, MD, PhD
Email: virjima@upmc.edu
Research Interests / Keywords:
Tumor markers; endocrine assays for intra-operative patient management; clinical laboratory automation and robotics; information management in clinical laboratories.

Andreas Vogt, PhD
Email: avogt@pitt.edu
Research Interests / Keywords:
Discovery of new therapeutic agents; mitogen-activated protein kinase phosphatases

Craig Wilcox, PhD
Email: daylite@pitt.edu
Research Interests / Keywords:
New methods for chemical discovery; models for protein folding; physical organic chemistry of solid phase synthesis

Clayton Wiley, MD, PhD
Email: wiley1@pitt.edu
Research Interests / Keywords:
Pathogenesis of neurodegenerative diseases and in particular on viral and age-induced nervous system diseases
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Wen Xie, MD, PhD
Email: wex6@pitt.edu
Research Interests / Keywords:
Drug metabolizing enzymes and transporters; orphan nuclear receptor-mediated regulation of genes View More

Herbert Zeh, MD
Email: zehxhx@upmc.edu
Research Interests / Keywords:
Pancreas surgery; surgical oncology View More

Kristin Zorn, MD
Email: kzorn@mail.magee.edu
Research Interests / Keywords:
Ovarian cancer; endometrial cancer

Daniel Zuckerman, PhD
Email: ddmmzz@pitt.edu
Research Interests / Keywords:
Development of algorithms and software to study dynamical biomolecular processes