University of Pittsburgh Cancer Institute (UPCI)

Program Members

Bennett Van Houten Bennett Van Houten, PhD (Co-Leader)
Email: vanhoutenb@upmc.edu
Research Interests / Keywords:
DNA repair; cancer pharmacology; drug discovery

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Zhou Wang Zhou Wang, PhD (Co-Leader)
Email: wangz2@upmc.edu
Research Interests / Keywords:
Androgen action in prostate cancer

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Gerard Apodaca Gerard Apodaca, PhD
Email: gla6@pitt.edu
Research Interests / Keywords:
Cell biology; uroepithelium; kidney epithelium; rho family GTPases; exocytosis; endocytosis

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Karen Arndt Karen Arndt, PhD
Email: arndt@pitt.edu
Research Interests / Keywords:
Transcriptional control

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Dean Bacich Dean Bacich, PhD
Email: djb26@pitt.edu
Research Interests / Keywords:
Mechanisms and models of prostate carcinogenesis

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Ivet Bahar Ivet Bahar, PhD
Email: bahar@pitt.edu
Research Interests / Keywords:
Structural biophysics; drug discovery; systems biology

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Mingfeng Bai Mingfeng Bai, PhD
Email: baim@upmc.edu
Research Interests / Keywords:
Contrast agent development; preclinical optical imaging; development and biomedical imaging of targeted molecular probes for early diagnosis of cancers

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Christopher Bakkenist Christopher Bakkenist, PhD
Email: cjb38@pitt.edu
Research Interests / Keywords:
Cancer pharmacology; DNA repair

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Takis (Panayiotis) Benos Takis (Panayiotis) Benos, PhD
E-mail: benos@pitt.edu
Research Interests / Keywords:
Computational genomics; systems biology

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Kara Bernstein Kara Bernstein, PhD
Email: karab@pitt.edu
Research Interests / Keywords:
DNA repair

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Jeffrey Brodsky Jeffrey Brodsky, PhD
Email: jbrodsky@pitt.edu
Research Interests / Keywords:
Protein quality control

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Marcel Bruchez Marcel Bruchez, PhD
Email: bruchez@cmu.edu
Research Interests / Keywords:
Fluorescence; biological microscopy; imaging; light-harvesting structures; biosensors; single molecule biophysics; protein translation; protein folding; protein trafficking

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J. Richard Chaillet J. Richard Chaillet, MD, PhD
Email: chaillet@pitt.edu
Research Interests / Keywords:
Genomic imprinting; epigenetic inheritance; embryonic stem cells; DNA methylation

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Marie DeFrances Marie DeFrances, MD, PhD
Email: defrancesmc@upmc.edu
Research Interests / Keywords:
PI3-kinase signaling

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Donald DeFranco Donald DeFranco, PhD
Email: dod1@pitt.edu
Research Interests / Keywords:
Receptor pharmacology; neuropharmacology; signal transduction

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Andrew Duncan Andrew Duncan, PhD
Email: duncanaw@upmc.edu
Research Interests / Keywords:
Hepatocellular carcinoma; liver development, homeostasis and regeneration

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Farzad Esni Farzad Esni, PhD
Email: Farzad.Esni@chp.edu
Research Interests / Keywords:
Genetics of pancreatic cancer; hypoxia

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Ferruccio Galbiati Ferruccio Galbiati, PhD
Email: feg5@pitt.edu
Research Interests / Keywords:
Cancer pharmacology; signal transduction

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Deborah Galson Deborah Galson, PhD
Email: galson@pitt.edu
Research Interests / Keywords:
Multiple myeloma; signal transduction; bone biology

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Madhavi Ganapathiraju Madhavi Ganapathiraju, PhD
Email: madhavi+web@pitt.edu
Research Interests / Keywords:
Systematic discovery of protein-protein interactions; host-pathogen systems biology

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Yang Hong Yang Hong, PhD
Email: yhong@pitt.edu
Research Interests / Keywords:
Cell polarity; genetics

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Johnny Huard Johnny Huard, PhD
Email: jhuard@pitt.edu
Research Interests / Keywords:
Stem cells; gene therapy

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William LaFramboise William LaFramboise, PhD
Email: laframboisewa@upmc.edu
Research Interests / Keywords:
Clinical genomics; next generation sequencing; targeted deep sequencing; cancer stem cells

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Li Lan Li Lan, MD, PhD
Email: lil64@pitt.edu
Research Interests / Keywords:
DNA damage and repair; effects of chromatin remodeling and histone modifications on DNA repair pathways

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Byeong-Chel Lee Byeong-Chel Lee, PhD
Email: leeb4@upmc.edu
Research Interests / Keywords:
Molecular mechanisms of hematopoietic stem cell senescence; breast cancer cell metastasis

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Yong Lee Yong Lee, PhD
Email: leeyj@upmc.edu
Research Interests / Keywords:
Metabolic oxidative stress-induced signal transduction pathways; targeted cancer therapy

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Photo Unavailable Yang Liu, PhD
Email: liuy10@upmc.edu
Research Interests / Keywords:
Biomedical optical imaging and spectroscopy; early cancer diagnosis, surveillance and prevention

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Xinghua Lu Xinghua Lu, MD, PhD
Email: xinghua@pitt.edu
Research Interests / Keywords:
Systems biology approaches to modeling cellular signal transduction pathways based on multiple sources of "omics" scale data, and their application in cancer

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Peter Lucas Peter Lucas, MD, PhD
Email: lucaspc@upmc.edu
Research Interests / Keywords:
Chronic inflammation; NF-kB; signal transduction; carcinogenesis

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Jianhua Luo Jianhua Luo, MD, PhD
Email: luojh@pitt.edu
Research Interests / Keywords:
Prostate cancer gene expression; invasion and metastasis

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Linda McAllister-Lucas Linda McAllister-Lucas, MD, PhD
Email: linda.mcallister@chp.edu
Research Interests / Keywords:
Signal transduction; inflammation; G protein-coupled receptor (GPCR); NF-kB; oncogenesis

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George Michalopoulos George Michalopoulos, MD, PhD
Email: michalopoulosgk@upmc.edu
Research Interests / Keywords:
Growth factors and receptors in hepatocytes; growth regulation of human hepatocytes; hepatic carcinogenesis

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Satdarshan (Paul) Monga Satdarshan (Paul) Monga, MD
Email: mongass@upmc.edu
Research Interests / Keywords:
Wnt/beta-catenin, HGF/Met, EGF, PDGF and other signaling pathways; molecular basis of liver growth and development; hepatic physiology and pathology

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Joel Nelson Joel Nelson, MD
Email: nelsonjb@upmc.edu
Research Interests / Keywords:
Prostate cancer; urinary tract malignancies; hormone refractory cancer

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Photo Unavailable Robert Nicholls, PhD
Email: rdn4@pitt.edu
Research Interests / Keywords:
Genomic imprinting; Prader-Willi and Angelman syndromes

Patricia Opresko Patricia Opresko, PhD
Email: plo4@pitt.edu
Research Interests / Keywords:
Cancer and aging; DNA damage, repair, and replication; DNA helicases; Werner syndrome; telomeres and telomere-binding proteins; DNA polymerases; mutagenesis

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Roderick O'Sullivan Roderick O'Sullivan, PhD
Email: osullivanr@upmc.edu
Research Interests / Keywords:
Structural and epigenetic functions of human telomeres; aging and cancer

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Hongjiao Ouyang Hongjiao Ouyang, DDS, PhD, DMD
Email: ouyangh@upmc.edu
Research Interests / Keywords:
Cellular and molecular mechanisms underlying bone development, maintenance, and disease

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Bruce Pitt Bruce Pitt, PhD
Email: brucep@pitt.edu
Research Interests / Keywords:
Molecular and cellular biology of the lung; gene therapy

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Edward Prochownik Edward Prochownik, MD, PhD
Email: procev@chp.edu
Research Interests / Keywords:
Regulation of and by the c-Myc oncoprotein; evaluation of molecular inhibitors of the c-Myc oncoprotein

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J. Peter Rubin J. Peter Rubin, MD
Email: rubipj@upmc.edu
Research Interests / Keywords:
Stem cell-based therapies; adipose (fat) metabolism

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Gerald Schatten Gerald Schatten, PhD
Email: gps15@pitt.edu
Research Interests / Keywords:
Stem cells; gene therapy; human reproduction and development; breast and ovarian cancers

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Martin Schmidt Martin Schmidt, PhD
Email: mcs2@pitt.edu
Research Interests / Keywords:
Cellular metabolism; signal transduction pathways

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Robert Sobol Robert Sobol, PhD
Email: rwsobol@mac.com
Research Interests / Keywords:
DNA repair; cancer pharmacology; drug discovery

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Donna Beer Stolz Donna Beer Stolz, PhD
Email: dstolz@pitt.edu
Research Interests / Keywords:
Growth factor signaling; angiogenesis; liver regeneration and transplantation

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Daolin Tang Daolin Tang, MD, PhD
Email: tangd2@upmc.edu
Research Interests / Keywords:
Role of HMGB1 in autophagy, apoptosis, and cancer

Gary Thomas Gary Thomas, PhD
Email: thomasg@pitt.edu
Research Interests / Keywords:
Signal transduction; cell membrane traffic; cancer biology; viral pathogenesis

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George Tseng George Tseng, ScD
Email: ctseng@pitt.edu
Research Interests / Keywords:
Statistical applications of genomics and bioinformatics

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Yong Wan Yong Wan, PhD
Email: yow4@pitt.edu
Research Interests / Keywords:
Regulation of intracellular signaling and gene expression; DNA repair; cell cycle control

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Hong Wang Hong Wang, PhD
Email: how8@pitt.edu
Research Interests / Keywords:
Survival analysis and statistics in cancer biomarker research; radiation survival analysis

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Simon Watkins Simon Watkins, PhD
Email: swatkins@pitt.edu
Research Interests / Keywords:
Cellular organization; cell-cell communications; cell imaging

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Daniel Weeks Daniel Weeks, PhD
Email: weeks@pitt.edu
Research Interests / Keywords:
Statistical human genetics; gene mapping

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Kurt Weiss Kurt Weiss, MD
Email: weiskr@upmc.edu
Research Interests / Keywords:
Musculoskeletal oncology; cancer stem cells

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John Woolford John Woolford, PhD
Email: jw17@andrew.cmu.edu
Research Interests / Keywords:
Assembly of ribosomes in eukaryotes

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Cary (Chuanyue) Wu Cary (Chuanyue) Wu, PhD
Email: carywu@pitt.edu
Research Interests / Keywords:
Cell-matrix adhesion; signal transduction

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Jian Yu Jian Yu, PhD
Email: yuj2@upmc.edu
Research Interests / Keywords:
Apoptosis regulation and the role of the Bcl-2 protein family in cancer biology and therapy

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Reza Zarnegar Reza Zarnegar, PhD
Email: rezazar@pitt.edu
Research Interests / Keywords:
Hepatocyte Growth Factor (HGF); physiological and pathological role of the HGF/Met axis in normal tissue homeostasis and disease processes including cancer

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Lin Zhang Lin Zhang, PhD
Email: zhanglx@upmc.edu
Research Interests / Keywords:
Protein kinases and phosphatases; cancer pharmacology

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