University of Pittsburgh Cancer Institute (UPCI)

Steffi Oesterreich, PhD (Co-Leader)
Email: oesterreichs@upmc.edu
Research Interests / Keywords:
Molecular mechanism and clinical relevance of endocrine response in breast cancer; cancer pharmacology View More

Bennett Van Houten, PhD (Co-Leader)
Email: vanhoutenb@upmc.edu
Research Interests / Keywords:
DNA repair; cancer pharmacology; drug discovery View More

Karen Arndt, PhD
Email: arndt@pitt.edu
Research Interests / Keywords:
Transcriptional control View More

Ivet Bahar, PhD
Email: bahar@pitt.edu
Research Interests / Keywords:
Structural biophysics; drug discovery; systems biology View More

Mingfeng Bai, PhD
Email: baim@upmc.edu
Research Interests / Keywords:
Contrast agent development; preclinical optical imaging; development and biomedical imaging of targeted molecular probes for early diagnosis of cancers View More

Christopher Bakkenist, PhD
Email: cjb38@pitt.edu
Research Interests / Keywords:
Cancer pharmacology; DNA repair View More

Takis (Panayiotis) Benos, PhD
E-mail: benos@pitt.edu
Research Interests / Keywords:
Computational genomics; systems biology
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Kara Bernstein, PhD
Email: karab@pitt.edu
Research Interests / Keywords:
DNA repair View More

Jeffrey Brodsky, PhD
Email: jbrodsky@pitt.edu
Research Interests / Keywords:
Protein quality control View More

Tao Cheng, MD
Email: chentx@upmc.edu
Research Interests / Keywords:
Cancer stem cells; hematologic malignancies View More

Marie DeFrances, MD, PhD
Email: defrancesmc@upmc.edu
Research Interests / Keywords:
PI3-kinase signaling View More

Donald DeFranco, PhD
Email: dod1@pitt.edu
Research Interests / Keywords:
Receptor pharmacology; neuropharmacology; signal transduction View More

Ferruccio Galbiati, PhD
Email: feg5@pitt.edu
Research Interests / Keywords:
Cancer pharmacology; signal transduction View More

Deborah Galson, PhD
Email: galson@pitt.edu
Research Interests / Keywords:
Multiple myeloma; signal transduction; bone biology View More

Madhavi Ganapathiraju, PhD
Email: madhavi+web@pitt.edu
Research Interests / Keywords:
Systematic discovery of protein-protein interactions; host-pathogen systems biology View More

Xin Huang, PhD
Email: huangx2@upmc.edu
Research Interests / Keywords:
Hypoxia in cancer; cancer genetics
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Li Lan, MD, PhD
Email: lil64@pitt.edu
Research Interests / Keywords:
DNA damage and repair; effects of chromatin remodeling and histone modifications on DNA repair pathways
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Adrian Lee, PhD
Email: leeav@upmc.edu
Research Interests / Keywords:
Organ pharmacology; breast cancer; steroid receptors; growth factor signaling View More

Byeong-Chel Lee, PhD
Email: leeb4@upmc.edu
Research Interests / Keywords:
Molecular mechanisms of hematopoietic stem cell senescence; breast cancer cell metastasis View More

Yong Lee, PhD
Email: leeyj@upmc.edu
Research Interests / Keywords:
Metabolic oxidative stress-induced signal transduction pathways; targeted cancer therapy View More

Sanford Leuba, PhD
Email: leuba@pitt.edu
Research Interests / Keywords:
Regulation of intracellular signaling and gene expression; chromatin; DNA repair; cell cycle control View More

Xinghua Lu, MD, PhD
Email: xinghua@pitt.edu
Research Interests / Keywords:
Systems biology approaches to modeling cellular signal transduction pathways based on multiple sources of "omics" scale data, and their application in cancer View More

George Michalopoulos, MD, PhD
Email: michalopoulosgk@upmc.edu
Research Interests / Keywords:
Growth factors and receptors in hepatocytes; growth regulation of human hepatocytes; hepatic carcinogenesis View More

Satdarshan (Paul) Monga, MD
Email: mongass@upmc.edu
Research Interests / Keywords:
Wnt/beta-catenin, HGF/Met, EGF, PDGF and other signaling pathways; molecular basis of liver growth and development; hepatic physiology and pathology View More

Satoshi Nakajima, PhD
Email: san48@pitt.edu
Research Interests / Keywords:
Genome stability; DNA damage and repair View More

Robert Nicholls, PhD
Email: rdn4@pitt.edu
Research Interests / Keywords:
Genomic imprinting; Prader-Willi and Angelman syndromes

Yuri Nikiforov, MD, PhD
Email: nikiforovye@upmc.edu
Research Interests / Keywords:
Molecular mechanisms of radiation-induced carcinogenesis and chromosomal rearrangements in human cells; molecular basis of thyroid cancer View More

Patricia Opresko, PhD
Email: plo4@pitt.edu
Research Interests / Keywords:
Cancer and aging; DNA damage, repair, and replication; DNA helicases; Werner syndrome; telomeres and telomere-binding proteins; DNA polymerases; mutagenesis View More

Edward Prochownik, MD, PhD
Email: procev@chp.edu
Research Interests / Keywords:
Regulation of and by the c-Myc oncoprotein; evaluation of molecular inhibitors of the c-Myc oncoprotein View More

Aleksandar Rajkovic, MD, PhD
Email: rajkovic@upmc.edu
Research Interests / Keywords:
Women's health; reproductive tract cancers; epidemiology; reproductive genetics; ovarian cancer View More

Robert Redner, MD
Email: rednerrl@upmc.edu
Research Interests / Keywords:
Acute promyelocytic leukemia; acute myeloid leukemia; myelodysplastic syndromes; malignant and non-malignant hematology View More

Pedro Rodriguez-Collazo, PhD
Email: pedrorc@pitt.edu
Research Interests / Keywords:
Chromatin; epigenetic control of chromatin-associated processes View More

Partha Roy, PhD
Email: par19@pitt.edu
Research Interests / Keywords:
Actin-binding proteins in tumor cell invasion and metastasis View More

Martin Schmidt, PhD
Email: mcs2@pitt.edu
Research Interests / Keywords:
Cellular metabolism; signal transduction pathways View More

Thomas Smithgall, PhD
E-mail: tsmithga@pitt.edu
Research Interests / Keywords:
Non-receptor protein-tyrosine kinase structure, regulation, and signal transduction in cancer, AIDS, and embryonic stem cell biology
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Robert Sobol, PhD
Email: rws9@pitt.edu
Research Interests / Keywords:
DNA repair; cancer pharmacology; drug discovery View More

Richard Steinman, MD, PhD
Email: steinman@pitt.edu
Research Interests / Keywords:
Hematopoietic stem cells; cancer and cellular differentiation View More

Donna Beer Stolz, PhD
Email: dstolz@pitt.edu
Research Interests / Keywords:
Growth factor signaling; angiogenesis; liver regeneration and transplantation View More

Steven Swerdlow, MD
Email: swerdlowsh@upmc.edu
Research Interests / Keywords:
B-cell lymphomas; post-transplant lymphoproliferative disorders; plasmacytoid dendritic cells in reactive lymph nodes; high throughput cytogenetic testing View More

Yong Wan, PhD
Email: yow4@pitt.edu
Research Interests / Keywords:
Regulation of intracellular signaling and gene expression; DNA repair; cell cycle control View More

Hong Wang, PhD
Email: how8@pitt.edu
Research Interests / Keywords:
Survival analysis and statistics in cancer biomarker research; radiation survival analysis View More

Simon Watkins, PhD
Email: swatkins@pitt.edu
Research Interests / Keywords:
Cellular organization; cell-cell communications; cell imaging View More

John Woolford, PhD
Email: jw17@andrew.cmu.edu
Research Interests / Keywords:
Assembly of ribosomes in eukaryotes View More

Jian Yu, PhD
Email: yuj2@upmc.edu
Research Interests / Keywords:
Apoptosis regulation and the role of the Bcl-2 protein family in cancer biology and therapy View More

Reza Zarnegar, PhD
Email: rezazar@pitt.edu
Research Interests / Keywords:
Hepatocyte Growth Factor (HGF); physiological and pathological role of the HGF/Met axis in normal tissue homeostasis and disease processes including cancer View More

Lin Zhang, PhD
Email: zhanglx@upmc.edu
Research Interests / Keywords:
Protein kinases and phosphatases; cancer pharmacology View More