University of Pittsburgh Cancer Institute (UPCI)

Overview

Director: Anna Lokshin, PhD

The versatile laboratory multianalyte profiling (LabMAP™) system developed by Luminex Corporation, located in Austin, Texas, is a flexible, easy-to-use protein analysis system that permits the simultaneous quantitative analysis of up to 100 different proteins, peptides, or DNA molecules in a single microtiter well. This multiplexing feature allows one to obtain a wealth of information using a minimum amount of sample. Multiplexing enables a comprehensive overview of complex biological systems and the inclusion of in-process controls. In addition, sample volume requirements are reduced and assay throughput is dramatically increased. Potential applications include:

• functional genomics
• validation of drug leads
• secondary screening
• absorption and distribution
• metabolism
• high-throughput ELISA and Western blot assays.

With the LUMINEX suspension array system you can:

• Quantitate up to 100 protein targets from culture media, sera, and other matrices simultaneously
• Automatically analyze up to 96 samples in 60 minutes (general format: 88 sample wells + 8 standard wells)
• Dramatically increase the amount of useful data