University of Pittsburgh Cancer Institute (UPCI)

Overview

The overarching mission of the UPCI Head and Neck Cancer Program (HNCP) is to advance the prevention, detection and treatment of this malignancy through translation of basic discoveries from member laboratories into clinical trials and to take observations from the clinic back to the bench to elucidate mechanisms. To achieve this goal, the program is focused on promoting and facilitating collaborative interactions and innovative discoveries among investigators along the entire continuum of basic, translational and clinical HNC research. Translational studies are also facilitated through a National Cancer Institute (NCI)-supported Specialized Program for Research Excellence (SPORE) grant in Head and Neck Cancer.

HNCP research is focused within three main themes:

  1. Window-of-Opportunity Platform Trials
  2. Targeting Resistance Mechanisms
  3. Precision Genomic Medicine