University of Pittsburgh Cancer Institute (UPCI)

Leadership

Jennifer Rubin Grandis, MD, FACS

Jennifer Rubin Grandis, MD, FACS, is a Professor in the Department of Otolaryngology, with a secondary appointment in the Department of Pharmacology at the University of Pittsburgh School of Medicine, and serves as Co-Leader of the Head and Neck Cancer Program at the University of Pittsburgh Cancer Institute. Dr. Grandis' basic science laboratory is dedicated to the study of EGFR signaling pathways in squamous cell carcinoma of the head and neck (SCCHN). Her research interests include G-protein-coupled receptor transactivation of EGFR, therapeutic targeting of EGFR and STATs in SCCHN patients, and determining the mechanism(s) of resistance to strategies that block this growth factor receptor. Dr. Grandis completed medical school, residencies in otolaryngology and surgery, and a fellowship in infectious disease at the University of Pittsburgh School of Medicine. During this time she received many awards and distinctions, including the Kenneth H. Hinderer Award in Otolaryngology and the Leo H. Criep Award in Medicine. Dr. Grandis has contributed numerous articles and abstracts to the scientific literature and holds patents for novel concepts pertaining to cancer treatments and diagnostics. She maintains membership in a number of professional societies, including the American Society for Clinical Investigation, American Academy of Otolaryngology-Head and Neck Surgery, American Medical Association, American Association for Cancer Research, and Women in Cancer Research. She is a fellow of the American College of Surgeons and the American Laryngological, Rhinological, and Otological (Triologic) Society. She received an American Cancer Society Clinical Research Professorship in 2008.

Department website: http://www.pharmacology.us/Faculty.aspx?FacultyID=48