Head and Neck Cancer Program (HNCP)

Overview

The Head and Neck Cancer Program (HNCP) provides the framework for a group of basic science investigators, clinicians, and physician scientists who are dedicated to elucidating the biology of head and neck cancer, with the goal of designing and implementing new strategies to prevent, detect, and treat this malignancy. The central mission of the HNCP is to improve the outcome of patients with squamous cell carcinoma of the head and neck (SCCHN). To accomplish this mission, HNCP members: (1) participate in laboratory research to increase our understanding of the biology of head and neck cancer, with special emphasis on elucidating the factors that contribute to SCCHN susceptibility, progression, and response to therapy; (2) initiate innovative clinical trials to test the hypotheses delineated in preclinical models; (3) recruit new investigators to the field of SCCHN; and (4) train young investigators in translational SCCHN research approaches. These objectives are accomplished through research funded by individual R01 grants, a SPORE P50 grant in head and neck cancer, and interactions with program projects, in addition to a pilot studies program and an NCI-sponsored training grant (T32) to support basic research training in head and neck oncology. Our investigators are highly productive, and collaboration is illustrated by frequent co-authorship among members of the Program and with members of other UPCI programs. HNCP members meet weekly to discuss patient management issues and recruitment to ongoing clinical studies in addition to a monthly research seminar. Overall, the HNCP serves to facilitate high quality translational research by encouraging and supporting collaborative interactions among clinicians and scientists.