Overview

The Basic Genomics and Proteomics Facility (BGPF) provides state-of-the-art genomic and proteomic technologies to UPCI investigators for basic research applications. The services span a wide range of technologies including cytogenetics, DNA sequencing, DNA and RNA isolation, Serial Analysis of Gene Expression (SAGE) library production, SNP genotyping, STRP genotyping, Microarray analysis (Affymetrix, CodeLink, and custom arrays), Quantitative RT-PCR, Difference Gel Electrophoresis, Ciphergen Proteinchip Profiling, Protein identification and sequencing.

The BGPF is a new facility that was formed by integrating four preexisting facilities: the Genomics and Proteomics Core Laboratories of the University of Pittsburgh Schools of the Health Sciences, the UPCI DNA Sequencing Facility, the UPCI Mass Spectrometry Facility and the UPCI Cytogenetics Facility. This scientific and administrative restructuring has made greatly expanded services and expert consultative assistance available at discounted prices to UPCI investigators. The laboratories are equipped with state-of the-art instrumentation and provide a variety of standardized and customized genomic and proteomic analyses to UPCI researchers, as well as other University investigators.

The goals of the BGPF are:

  1. To provide access to genomics technologies for basic cancer research and help investigators determine which technologies are most applicable for their research
  2. To provide access to proteomics technologies for basic cancer research and help investigators determine which technologies are most applicable for their research
  3. To provide access to tools and expertise in genomic and proteomic data analysis and interpretation