University of Pittsburgh Cancer Institute (UPCI)

Program Members

Patrick Moore, MD, MPH Patrick Moore, MD, MPH (Leader)
Email: psm9@pitt.edu
Research Keywords:
Human tumor virology (KSHV, MCV and digital transcriptome subtraction)

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Velpandi Ayyavoo, PhD Velpandi Ayyavoo, PhD
Email: velpandi@pitt.edu
Research Keywords:
HIV infection; microRNAs; viral and host gene expression; antiviral therapy; biomarker discovery; drug development

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Simon Barratt-Boyes, PhD, BVSc Simon Barratt-Boyes, PhD, BVSc
Email: smbb@pitt.edu
Research Keywords:
Dendritic cell dynamics in viral infections; vector-based vaccines for viral infections

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Yuan Chang, MD Yuan Chang, MD
Email: yc70@pitt.edu
Research Keywords:
Tumor viruses; Kaposi's sarcoma associated herpesvirus (KSHV); Merkel cell polyomavirus (MCV); digital transcriptome subtraction; tumor virus discovery

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James Conway, PhD James Conway, PhD
Email: jxc100@pitt.edu
Research Keywords:
Structure and function of macromolecular complexes; virus capsids; cryo-electron microscopy; herpesvirus; protein structure

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Carolyn Coyne, PhD Carolyn Coyne, PhD
Email: coynec2@pitt.edu
Research Keywords:
Enteroviruses; innate immunity

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Ross Cranston, MD, FRCP Ross Cranston, MD, FRCP
Email: rdc27@pitt.edu
Research Keywords:
Anal cancer; squamous cell cancer; HIV; men who have sex with men; human papillomavirus; HPV; dysplasia

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Neal A. DeLuca, PhD Neal A. DeLuca, PhD
Email: ndeluca@pitt.edu
Research Keywords:
HSV-1-mediated regulation of gene expression

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Andrea Gambotto, MD Andrea Gambotto, MD
Email: gambottoa@upmc.edu
Research Keywords:
Development of adenoviral vector based vaccines for HIV-1 and influenza

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Joseph C. Glorioso III, PhD Joseph C. Glorioso III, PhD
Email: glorioso@pitt.edu
Research Keywords:
Using HSV vectors for studies of cellular gene functions and for analysis of embryonic stem cell differentiation

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Paola Grandi, PhD Paola Grandi, PhD
Email: pag24@mgb.pitt.edu
Research Keywords:
Gene therapy for brain tumors using HSV-based vectors; molecular targeting to tumor cells; molecular mechanisms of tumor cell migration; miRNAs in cancer progression

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Phalguni Gupta, PhD Phalguni Gupta, PhD
Email: pgupta1@pitt.edu
Research Keywords:
Cellular and molecular basis of HIV pathogenesis and transmission; development of novel vaccine candidates and microbicides against HIV; non-lytic CD8+T cell mediated HIV suppression; international study on molecular epidemiology and pathogenesis of HIV in India and China

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Fred L. Homa, PhD Fred L. Homa, PhD
Email: flhoma@pitt.edu
Research Keywords:
Molecular basis of HSV-1 capsid assembly and DNA packaging

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Saleem A. Khan, PhD Saleem A. Khan, PhD
Email: khan@pitt.edu
Research Keywords:
Molecular biology and pathogenesis of human papillomaviruses (HPVs); role of microRNAs in HPV-associated cancers, and in aging; DNA helicases; replication of drug resistance and virulence plasmids of S. aureus and B. anthracis

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Paul (Kip) R. Kinchington, PhD Paul (Kip) R. Kinchington, PhD
Email: kinch@pitt.edu
Research Keywords:
HSV; VZV; herpes simplex virus; zoster; varicella; viral infection; viral latency; infectious eye disease; pain and post-herpetic neuralgia; neuronal infection

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Diana M. Metes, MD Diana M. Metes, MD
Email: metesdm@upmc.edu
Research Keywords:
Epstein-Barr virus (EBV); adaptive immunity; post-transplant lymphoproliferative disorder (PTLD); T cell memory; dendritic cells

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Joseph T. Newsome, DVM Joseph T. Newsome, DVM
Email: jnewsome@pitt.edu
Research Keywords:
Immunopathology; vaccinology; dermatopathology; papillomavirus; infectious disease animal modeling

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Liron Pantanowitz, MD Liron Pantanowitz, MD
Email: pantanowitzl@upmc.edu
Research Keywords:
AIDS; cytopathology; HIV; informatics; Kaposi's sarcoma; lymphoma; viral-induced cancer

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James M. Pipas, PhD James M. Pipas, PhD
Email: pipas@pitt.edu
Research Keywords:
Molecular biology of DNA tumor viruses; molecular mechanisms of tumorigenicity

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Todd A. Reinhart, ScD Todd A. Reinhart, ScD
Email: reinhar@pitt.edu
Research Keywords:
Role of chemokines in the pathogenesis of HIV-1 and SIV; basic biology and inhibition of chemokines; roles played by lymphatic endothelial cells in infectious diseases and vaccines; vaccines for HIV-1, influenza, and cancer

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Charles R. Rinaldo, PhD Charles R. Rinaldo, PhD
Email: rinaldo@pitt.edu
Research Keywords:
Cellular immunity to human immunodeficiency virus (HIV), Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8), and hepatitis C virus (HCV)

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Saumendra N. Sarkar, PhD Saumendra N. Sarkar, PhD
Email: saumen@pitt.edu
Research Keywords:
Virus-mediated innate immune response and Toll-like receptor signaling

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Kathy Shair, PhD Kathy Shair, PhD
Email: kas361@pitt.edu
Research Keywords:
Epstein-Barr virus; nasopharyngeal carcinoma; B cell lymphoma; cancer virology

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Thomas E. Smithgall, PhD Thomas E. Smithgall, PhD
Email: tsmithga@pitt.edu
Research Keywords:
Protein-tyrosine kinases; Src-family kinase; Abl; Fes; AML; CML; myeloma; HIV; AIDS; drug discovery; chemical biology

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Stephen H. Thorne, PhD Stephen H. Thorne, PhD
Email: thornesh@upmc.edu
Research Keywords:
Oncolytic viral therapies; immunotherapies; vaccinia virus; small animal imaging; bioluminescence imaging; fluorescence imaging

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Clayton Wiley, MD, PhD Clayton Wiley, MD, PhD
Email: wiley1@pitt.edu
Research Keywords:
Viral infection; innate immune response; neurodegeneration; encephalitis; inflammation; macrophages

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Gutian Xiao, PhD Gutian Xiao, PhD
Email: xiaog2@upmc.edu
Research Keywords:
Signal transduction in immunity and tumorigenesis

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