University of Pittsburgh Cancer Institute (UPCI)

Program Members

Patrick Moore Patrick Moore MD, MPH (Leader)
Email: psm9@pitt.edu
Research Interests / Keywords:
Human tumor virology (KSHV, MCV and digital transcriptome subtraction)

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Velpandi Ayyavo Velpandi Ayyavo, PhD
Email: velpandi@pitt.edu
Research Interests / Keywords:
HIV-1 induced neuropathogenesis and immunopathogenesis; genome wide profiling of transcriptome and epigenetic regulators in HIV-1 disease progression; antiviral drug development and high content screening
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Simon Barrett-Boyes Simon Barratt-Boyes, PhD, BVSc
Email: smbb@pitt.edu
Research Interests / Keywords:
Dendritic cell dynamics in viral infections; vector-based vaccines for viral infections
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Takis (Panayiotis) Benos Takis (Panayiotis) Benos, PhD
Email: benos@pitt.edu
Research Interests / Keywords:
Computational genomics; systems biology
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Yuan Chang Yuan Chang, MD
Email: yc70@pitt.edu
Research Interests / Keywords:
Human tumor virology (KSHV, MCV and digital transcriptome subtraction)
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Carolyn Coyne Carolyn Coyne, PhD
Email: coynec2@pitt.edu
Research Interests / Keywords:
Enteroviruses; innate immunity
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Ross Cranston Ross Cranston, MD
Email: rdc27@pitt.edu
Research Interests / Keywords:
HPV associated anal dysplastic change in immunosuppressed individuals
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Neal DeLuca Neal DeLuca, PhD
Email: ndeluca@pitt.edu
Research Interests / Keywords:
HSV-1-mediated regulation of gene expression
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Anette Duensing Anette Duensing, MD
Email: aduensin@pitt.edu
Research Interests / Keywords:
Aneuploidy in cancer; centrosome anomalies; primary gastrointestinal stromal tumors

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Andrea Gambotto Andrea Gambotto, MD
Email: agamb@pitt.edu
Research Interests / Keywords:
Development of adenoviral vector based vaccines for HIV-1 and influenza
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Elodie Ghedin Elodie Ghedin, PhD
Email: elg21@pitt.edu
Research Interests / Keywords:
RNA virus evolution; molecular epidemiology; parasite genomics; metagenomics and virus discovery
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Joseph Glorioso Joseph Glorioso, PhD
Email: glorioso@pitt.edu
Research Interests / Keywords:
Using HSV vectors for studies of cellular gene functions and for analysis of embryonic stem cell differentiation
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Phalguni Gupta Phalguni Gupta, PhD
Email: pgupta1@pitt.edu
Research Interests / Keywords:
Cellular and molecular basis of HIV pathogenesis and transmission; development of novel vaccine candidates and microbicides against HIV; non-lytic CD8+T cell mediated HIV suppression; international study on molecular epidemiology and pathogenesis of HIV in India and China
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Fred Homa Fred Homa, PhD
Email: flhoma@pitt.edu
Research Interests / Keywords:
Molecular basis of HSV-1 capsid assembly and DNA packaging
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Bino John Bino John, PhD
Email: john@johnlab.org
Research Interests / Keywords:
Bioinformatics/computational and experimental methods to study disease-related gene functions
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Saleem Khan Saleem Khan, PhD
Email: khan@pitt.edu
Research Interests / Keywords:
Molecular biology and pathogenesis of human papillomaviruses (HPVs); role of microRNAs in HPV-associated cancers, and in aging; DNA helicases; replication of drug resistance and virulence plasmids of S. aureus and B. anthracis
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Paul Kinchington Paul Kinchington, PhD
Email: kinch@pitt.edu
Research Interests / Keywords:
Herpesvirus; protein kinases; virus latency; protein-serine-threonine kinases; viral regulatory proteins; virus replication; adenoviridae infections; antiviral agents
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Fadi Lakkis Fadi Lakkis, MD
Email: lakkisf@upmc.edu
Research Interests / Keywords:
Innate immunity; immunologic memory; T lymphocytes; cytokines; transplantation immunology; graft rejection
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Jianhua Luo Jianhua Luo, MD, PhD
Email: luojh@pitt.edu
Research Interests / Keywords:
Genome and gene expression study of malignancies, especially in understanding how prostate cancers obtain invasive and metastatic capability
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John Mellors John Mellors, MD
Email: mellors@dom.pitt.edu
Research Interests / Keywords:
HIV/AIDS; HIV drug resistance; antiretroviral therapy; HIV reservoirs and their elimination
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Malcolm Meyn Malcolm Meyn, PhD
Email: mam71@pitt.edu
Research Interests / Keywords:
Regulation of stem cell pluripotency and differentiation

Ronald Montelaro Ronald Montelaro, PhD
Email: rmont@pitt.edu
Research Interests / Keywords:
Viral immunology and vaccine development for evolving viruses
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Liron Pantanowitz Liron Pantanowitz, MD
Email: pantanowitzl@upmc.edu
Research Interests / Keywords:
Cytopathology; pathology informatics; HIV/AIDS
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James Pipas James Pipas, PhD
Email: pipas@pitt.edu
Research Interests / Keywords:
Molecular biology of DNA tumor viruses; molecular mechanisms of tumorigenicity
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Todd Reinhart Todd Reinhart, ScD
Email: reinhar@pitt.edu
Research Interests / Keywords:
Role of chemokines in the pathogenesis of HIV-1 and SIV; basic biology and inhibition of chemokines; roles played by lymphatic endothelial cells in infectious diseases and vaccines; vaccines for HIV-1, influenza, and cancer
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Charles Rinaldo Charles Rinaldo, PhD
Email: rinaldo@pitt.edu
Research Interests / Keywords:
Cellular immunity to human immunodeficiency virus (HIV), Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8), and hepatitis C virus (HCV)
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Adam Rosendorff Adam Rosendorff, MD
Email: adr34@pitt.edu
Research Interests / Keywords:
Epstein-Barr virus (EBV); induction of B-cell leukemogenesis in hematopoetic stem cell models
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Saumendra Sarkar Saumendra Sarkar, PhD
Email: saumen@pitt.edu
Research Interests / Keywords:
Virus-mediated innate immune response and Toll-like receptor signaling
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Thomas Smithgall Thomas Smithgall, PhD
Email: tsmithga@pitt.edu
Research Interests / Keywords:
Non-receptor protein-tyrosine kinase structure, regulation, and signal transduction in cancer, AIDS, and embryonic stem cell biology
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Stephen Strom Stephen Strom, PhD
Email: strom@pitt.edu
Research Interests / Keywords:
Chemical carcinogenesis and molecular mechanisms of growth control in human liver and prostate
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Stephen Thorne Stephen Thorne, PhD
Email: sht38@pitt.edu
Research Interests / Keywords:
Oncolytic viruses; optical tumor imaging; cancer immunotherapy
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Tianyi Wang Tianyi Wang, PhD
Email: tywang@pitt.edu
Research Interests / Keywords:
Hepatitis C virus; innate immunity; proteomics; host-pathogen interaction
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Clayton Wiley Clayton Wiley, MD, PhD
Email: wiley1@pitt.edu
Research Interests / Keywords:
Pathogenesis of neurodegenerative diseases and in particular on viral and age-induced nervous system diseases
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Gutian Xiao Gutian Xiao, PhD
Email: gux8@pitt.edu
Research Interests / Keywords:
Signal transduction in immunity and tumorigenesis
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