The UPCI Brain Tumor Program (BTP) is involved in basic, clinical, and translational research, and clinical care in neurooncology. Members are organized into six Research Interest Groups: (1) signal transduction inhibition/experimental therapeutics; (2) immunobiology and immunotherapy; (3) modulation of DNA repair-related drug resistance; (4) modulation of glioma angiogenesis and invasion by pharmacological interventions; (5) optimization of radiation response; and (6) oncoviral therapy.
Read more about the Brain Tumor Program
Research Themes:
Designing novel therapeutic combinations that incorporate inhibitors of cellular signaling pathways
Developing specific and potent immunotherapies, assisted by molecular targeting strategies
Inhibiting DNA repair mechanisms to overcome resistance to chemotherapy
Investigating molecular mechanisms of angiogenesis and invasion for potential pharmacological intervention
Examining strategies to optimize efficacy of radiation for the treatment of brain tumors
Enhancing the effectiveness of oncolytic virus-based cancer therapies
