April 2013 - Now Available at the UPCI Vector Core Facility: Breast Cancer Cell Lines Expressing Fluorescent Markers or Luciferase
Services of the UPCI Vector Core Facility have now expanded to include production of a number of MDA-MB-231 breast cancer cell lines that express various fluorescent or luciferase markers. These include lines with cell-wide expression of YFP, CFP, RFP, FP636, iRFP, or luciferase, as well as lines with targeted sub-cellular expression of fluorescent markers, such as in the cytosol, Golgi apparatus, endoplasmic reticulum, mitochondria, tubulin, etc. Please contact Rob Sobol at firstname.lastname@example.org or 412-623-7764, or visit the Vector Core Facility Services and Fees Section for more information.
March 2013 - Save the Date: The 25th Annual UPCI Scientific Retreat
The 25th annual UPCI Scientific Retreat will be held at the Petersen Events Center on June 14, 2013. Registration and poster abstract submission will open in May. Stay tuned for further announcements on the UPCI website.
September 2012 - New Small Animal PET/CT Imaging Suite Now Open at the Hillman
A brand new Siemens Inveon small animal PET/CT imager is now available for use in the recently renovated, multi-modality small animal imaging suite located behind the barrier of the UPCI Animal Facility at the Hillman Cancer Center. The expansion project to incorporate the new machine as well as a state-of-the-art radiochemistry laboratory was completed in September, offering the research community sophisticated PET/CT capabilities that complement the optical, ultrasound, and MR imaging instrumentation located in the same laboratory. These preclinical imaging resources, offered through the UPCI In Vivo Imaging Facility, are highly valuable for studying cancer biology and determining cancer therapy effectiveness. In addition, results can be rapidly translated into clinical applications.
To learn more about utilizing small animal PET/CT in your research, contact Dr. Carolyn Anderson.
August 2012 - New “Center for Bone Biology” forming at UPCI
Deborah L. Galson, PhD would like to invite you to become involved with the new Center for Bone Biology. The aim of this Center is to bring together researchers at the University of Pittsburgh, Carnegie Mellon University, and Duquesne University who are interested in any and all aspects of bone biology. The center has several purposes:
- to help investigators locate resources around Pittsburgh and to develop fruitful collaborations;
- to serve as a resource for researchers who find their work wandering unexpectedly into the field of bone biology; and
- to showcase the extensive bone-related research that is being conducted here in Pittsburgh.
Content for the Center's developing website (a future component of UPCI's website) may include such resources as:
- a list of members with links to their labs/centers;
- a schedule of bone-related seminars sponsored by the Center for Bone Biology and others in the area;
- individual member resources that might be beneficial to others/shared with collaborators, including instrumentation, technical expertise, and mice models; and
- information regarding bone cell and/or bone analyses methods.
If interested in becoming a member of the Center for Bone Biology, you are invited to participate in an organizational meeting being held on Tuesday, September 11, 2012 at 4pm in the Hillman Cancer Center 2nd Floor Conference Room, with the following goals:
- establish a seminar series and determine how it will be structured, where it will be held, and how often;
- gather ideas of what content should be included on the website;
- brainstorm about additional activities that would contribute to the overall aims of the Center; and
- create a governing structure.
If you are unable to attend but have suggestions/concepts, etc. that you would like to have discussed at the meeting, please email them to Dr. Deborah Galson.
May 2012 – Next Generation Sequencing Available at UPCI
The UPCI Cancer Biomarkers Facility (CBF) Clinical Sequencing Laboratory offers Life Technologies SOLiD and Ion Torrent sequencing systems for massively parallel sequencing of small nucleic acid fragments to generate nearly complete coverage of whole genomes at greater than 99% accuracy. Contact Dr. William LaFramboise for more information or to schedule a consultation.
April 2012 – Construction Begins to Expand Small Animal Imaging Capabilities at the Hillman
Renovations are underway to expand the multi-modality small animal imaging suite located behind the barrier of the UPCI Animal Facility at the Hillman Cancer Center. Installation of a new Siemens Inveon small animal PET/CT imager will complement the optical, ultrasound, and MR imaging instrumentation located in the same laboratory, enabling investigators to longitudinally image the same mice with multiple modalities. These preclinical imaging capabilities, offered through the UPCI In Vivo Imaging Facility, are highly valuable for studying cancer biology and determining cancer therapy effectiveness. In addition, results can be rapidly translated into clinical applications. Dr. Carolyn Anderson, an expert in the development of novel PET imaging agents that target cancer and cancer metastasis, will lead the small animal PET/CT efforts once installation of the Inveon is complete in summer 2012.
March 2012 – Save the Date: The 24th Annual UPCI Scientific Retreat
The 24th annual UPCI Scientific Retreat will be held at the University of Pittsburgh at Greensburg on June 21-22, 2012. Registration and poster abstract submission will open in May. Stay tuned for further announcements on the UPCI website.
January 2012 – New Fortessa Flow Cytometer is Ready for Use at the UPCI Cytometry Facility
The Fortessa is a four laser flow cytometer capable of detecting up to 13 distinct fluorochromes simultaneously. Along with traditional forward and side scatter, the Fortessa is equipped with a PMT dedicated to detection of forward scatter, making the Fortessa ideal for microparticle detection.
Learn more on the UPCI Cytometry Facility website, or contact Mike Meyer for more information or to set up a consultation.